Description

3-Iodo-4-Methoxybiphenyl is a high-purity, functionalized biphenyl derivative featuring both iodo and methoxy substituents. This compound serves as a versatile and critical advanced pharmaceutical intermediate (API) and a valuable building block in organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides, leveraging its biphenyl core for biological activity.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to construct complex biaryl systems.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for the construction of complex molecular architectures due to its two reactive sites.

Basic Information

Item	Details
Product Name	3-Iodo-4-Methoxybiphenyl
CAS No.	91718-20-6
Molecular Formula	C13H11IO
Molecular Weight	310.13 g/mol
Synonyms	4'-Methoxy-3-iodobiphenyl; 3-Iodo-4'-methoxy-1,1'-biphenyl; 4-Methoxy-3-iodobiphenyl; [1,1'-Biphenyl]-3-iodo-4-methoxy; Biphenyl, 3-iodo-4-methoxy-
EINECS	Contact for details

Quality Control

Our 3-Iodo-4-Methoxybiphenyl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.