Description

3-[(Z)-Butylidene]-5-Hydroxyisobenzofuran-1(3H)-One is a specialized organic compound belonging to the isobenzofuranone class, serving as a valuable synthetic intermediate. Its unique molecular structure, featuring a butylidene side chain and a hydroxyl group, makes it a critical building block for the synthesis of more complex molecules in advanced chemical research and development. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting specific biological pathways.
• Fine Chemical Synthesis: Used as a versatile building block for constructing complex organic frameworks in custom synthesis and process chemistry.
• Agrochemical Research: Intermediate in the development of new crop protection agents and specialty agrochemicals.
• Material Science: Potential monomer or additive in the research of advanced polymers and functional organic materials.
• Academic & Industrial R&D: Essential for chemical research in universities and corporate labs exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	3-[(Z)-Butylidene]-5-Hydroxyisobenzofuran-1(3H)-One
CAS No.	91652-78-7
Molecular Formula	C12H12O3
Molecular Weight	204.22 g/mol
Synonyms	5-Hydroxy-3-[(Z)-butylidene]isobenzofuran-1(3H)-one; 3-(Z)-Butylidene-5-hydroxy-1(3H)-isobenzofuranone; 3-Butylidene-5-hydroxyphthalide (Z-isomer); (Z)-3-Butylidene-5-hydroxyphthalide; 5-Hydroxy-3-butylidenephthalide; Light-sensitive phthalide derivative
EINECS	Contact for details

Quality Control

Our 3-[(Z)-Butylidene]-5-Hydroxyisobenzofuran-1(3H)-One is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, purity, and impurity profile. For projects requiring specific regulatory compliance, please contact our technical team to discuss custom synthesis and documentation support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.