Description

(Z)-2,4,4,4-Tetrafluorobut-2-En-1-Ol CAS NO 91600-37-2 is a fluorinated allylic alcohol building block of significant interest in advanced organic synthesis. Its unique structure, featuring a tetrafluoroalkene moiety adjacent to a hydroxyl group, makes it a versatile precursor for introducing fluorinated segments into target molecules. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, potentially improving metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where fluorine atoms can enhance activity and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or building block for specialty polymers and coatings with unique surface properties (e.g., low surface energy, chemical resistance).
• Liquid Crystal & OLED Materials: Incorporated into the synthesis of fluorinated components for electronic display and lighting applications.
• Fluorinated Surfactant Research: Acts as a starting material for developing new fluorosurfactants with specific performance characteristics.
• Medicinal Chemistry & SAR Studies: Employed to explore structure-activity relationships by introducing a rigid, lipophilic fluorinated group into lead compounds.

Basic Information

Product Name	(Z)-2,4,4,4-Tetrafluorobut-2-En-1-Ol
CAS No.	91600-37-2
Molecular Formula	C4H4F4O
Molecular Weight	144.07 g/mol
Synonyms	(Z)-2,4,4,4-Tetrafluoro-2-buten-1-ol; (Z)-Tetrafluorobut-2-ene-1-ol; 2,4,4,4-Tetrafluoro-2-buten-1-ol, (Z)-; (Z)-1,1,2,3,3,3-Hexafluoroprop-1-en-2-ylmethanol (related isomer); TFB-ol; Fluorinated butenol; Tetrafluorobuteneol; 91600-37-2
EINECS	Contact for details

Quality Control

Our (Z)-2,4,4,4-Tetrafluorobut-2-En-1-Ol is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0% (Area %)
Purity (HPLC)	≥ 95.0% (Area %)
Isomeric Purity (Z-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.