Description

4-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl))-Benzeneacetic Acid is a high-purity specialty chemical intermediate featuring a maleimide-substituted phenylacetic acid structure. This compound is valued for its dual functionality, enabling its use as a versatile building block in advanced organic synthesis and polymer chemistry. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted drug molecules, particularly those requiring maleimide groups for bioconjugation or as part of a heterocyclic pharmacophore.
• Polymer Modification: Used to introduce reactive maleimide sites into polymer backbones (e.g., polyethylene glycol, acrylics) for creating cross-linkable or functionalized materials.
• Bioconjugation Reagent: Enables the covalent attachment of drugs, probes, or peptides to antibodies, proteins, or nanoparticles via thiol-maleimide "click" chemistry.
• Agrochemical Synthesis: Serves as an intermediate in the development of novel herbicides, fungicides, or plant growth regulators.
• Advanced Material Research: Employed in R&D for creating specialty coatings, adhesives, or resins with tailored thermal and mechanical properties.
• Cross-linking Agent: Functions as a thermal or UV-activated cross-linker in specialty polymer formulations to enhance durability and performance.

Basic Information

Product Name	4-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl))-Benzeneacetic Acid
CAS No.	91574-45-7
Molecular Formula	C12H9NO4
Molecular Weight	231.20 g/mol
Synonyms	4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenylacetic Acid; 1-(4-Carboxymethylphenyl)maleimide; N-(4-Carboxymethylphenyl)maleimide; 4-(Maleimidophenyl)acetic Acid; 4-(Maleimido)phenylacetic Acid; [4-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-phenyl]-acetic Acid; 4-Maleimidophenylacetic Acid; 4-(N-Maleimido)phenylacetic Acid
EINECS	Contact for details

Quality Control

Our production of 4-(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl))-Benzeneacetic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, NMR, and IR spectroscopy for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.