Description

2-Hydroxy-3-Methylbut-3-Enoic Acid is a specialized organic acid featuring both hydroxyl and carboxylic acid functional groups on an unsaturated carbon skeleton. This unique structure makes it a valuable chiral building block and intermediate for synthesizing more complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for applications in asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic and neurological pathways.
• Asymmetric Synthesis: Utilized as a building block in stereoselective chemical reactions to construct complex molecules with defined three-dimensional structures.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, including advanced polymers, liquid crystals, and performance materials.
• Agrochemical Research: Investigated as an intermediate for developing new generation herbicides and plant growth regulators with improved efficacy.
• Flavor & Fragrance Chemistry: Used in the synthesis of complex esters and lactones that contribute to unique sensory profiles in high-value applications.
• Academic & Industrial R&D: Employed in chemical research for method development, catalysis studies, and exploring new reaction pathways.

Basic Information

Product Name	2-Hydroxy-3-Methylbut-3-Enoic Acid
CAS No.	91496-47-8
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	3-Methyl-2-hydroxybut-3-enoic acid; 2-Hydroxy-3-methyl-3-butenoic acid; β-Hydroxy-β-methylacrylic acid; 3-Methyl-2-hydroxy-3-butenoic acid; (E)-2-Hydroxy-3-methylbut-3-enoic acid (possible isomer); HMBEA; Contact for additional trade names.
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our standard grade for 2-Hydroxy-3-Methylbut-3-Enoic Acid typically meets a purity specification of ≥95% (by HPLC), with options for higher grades (≥98%, ≥99%) available to support critical research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.