Description

(2Z)-3-(4-tert-Butylphenyl)-3-Chloroprop-2-Enal CAS NO 91405-41-3 is a high-purity, synthetically valuable α,β-unsaturated aldehyde derivative. This compound serves as a critical chiral building block and advanced intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. Its unique structure, featuring both a reactive aldehyde group and a chlorinated alkene, makes it indispensable for researchers and process chemists developing active pharmaceutical ingredients (APIs), fine chemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of chiral drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used as a building block for developing novel pesticides, herbicides, and plant growth regulators with enhanced efficacy.
• Fine Chemical Production: Serves as a versatile intermediate for manufacturing specialty chemicals, flavors, and fragrances.
• Material Science Research: Employed in the development of advanced polymers and functional materials due to its polymerizable alkene and aldehyde functionalities.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, including asymmetric catalysis and cross-coupling reactions.

Basic Information

Product Name	(2Z)-3-(4-tert-Butylphenyl)-3-Chloroprop-2-Enal
CAS No.	91405-41-3
Molecular Formula	C₁₃H₁₅ClO
Molecular Weight	222.71 g/mol
Synonyms	(Z)-3-(4-tert-Butylphenyl)-3-chloroacrylaldehyde; 3-Chloro-3-(4-tert-butylphenyl)propenal; (2Z)-3-(4-tert-Butylphenyl)-3-chloroacrylaldehyde; 3-(4-tert-Butylphenyl)-3-chloro-2-propenal; (Z)-3-Chloro-3-(4-tert-butylphenyl)acrylaldehyde; 91405-41-3; p-tert-Butyl-β-chlorocinnamaldehyde
EINECS	Contact for details

Quality Control

Our (2Z)-3-(4-tert-Butylphenyl)-3-Chloroprop-2-Enal is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent isomeric composition. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach ambient temperature before opening to minimize moisture ingress. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Isomeric Purity (Z-Isomer)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.