Description

Dl-Threo-4-Fluoroglutamic Acid is a fluorinated derivative of the amino acid glutamic acid, serving as a critical chiral building block and biochemical probe. This compound is valued for its ability to modulate glutamate receptor activity and its utility in the synthesis of more complex bioactive molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors for drug discovery, metabolic studies, and the development of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutics, particularly those targeting neurological pathways.
• Biochemical Research: Used as a probe or substrate in enzymatic studies and metabolic pathway analysis related to glutamate function.
• Agrochemical Development: Serves as a precursor in the synthesis of advanced, fluorinated active ingredients for crop protection.
• Peptide Synthesis: Incorporated into custom peptides to study structure-activity relationships and enhance metabolic stability.
• Neuroscience Research: Utilized to investigate the role of glutamate transporters and receptors in cellular models.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Dl-Threo-4-Fluoroglutamic Acid
CAS No.	91383-47-0
Molecular Formula	C5H8FNO4
Molecular Weight	165.12 g/mol
Synonyms	4-Fluoro-DL-glutamic Acid; DL-4-Fluoroglutamic Acid; (2R*,4S*)- and (2S*,4R*)-4-Fluoroglutamic Acid; (±)-threo-4-Fluoroglutamate; 2-Amino-4-fluoropentanedioic Acid; Fluoroglutamic Acid; NSC 113928; DL-threo-4-Fluoroglutamate
EINECS	Contact for details

Quality Control

Our Dl-Threo-4-Fluoroglutamic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Specified ratio of diastereomers
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.