Description

Benzeneacetonitrile, α-Hydroxy-4-(1-Methylethyl)- (9Ci) is a specialized organic nitrile compound featuring a hydroxyl-substituted benzylic carbon. This unique molecular structure makes it a valuable versatile building block and key synthetic intermediate in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing chiral benzylic alcohol or nitrile functionalities.
• Agrochemical Synthesis: Used in the development and production of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Acts as a building block for dyes, pigments, and other performance chemicals requiring specific aromatic substitution patterns.
• Ligand and Catalyst Development: Employed in research for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or modifying agent for specialty polymers and advanced organic materials.

Basic Information

Product Name	Benzeneacetonitrile, α-Hydroxy-4-(1-Methylethyl)- (9Ci)
CAS No.	91132-18-2
Molecular Formula	C11H13NO
Molecular Weight	175.23 g/mol
Synonyms	2-Hydroxy-2-(4-isopropylphenyl)acetonitrile; α-Hydroxy-4-isopropylbenzeneacetonitrile; 4-Isopropylmandelonitrile; (4-Isopropylphenyl)(hydroxy)acetonitrile; 2-(4-Isopropylphenyl)-2-hydroxyacetonitrile; p-Isopropylmandelonitrile; Hydroxy(4-propan-2-ylphenyl)acetonitrile
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and purity. Our products undergo comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and meet stringent purity specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment. Our commitment to quality supports compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.