Description

(S)-4-Tosyloxy-1,2-Epoxybutane is a high-purity chiral epoxide building block, essential for the stereoselective synthesis of complex organic molecules. Its value lies in its role as a key electrophilic intermediate for introducing functionalized butane chains with defined stereochemistry. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of chiral drug candidates, particularly for cardiovascular and antiviral therapeutics.
• Agrochemical Synthesis: Used to construct chiral active ingredients for herbicides, fungicides, and plant growth regulators.
• Chiral Ligand & Catalyst Development: Serves as a starting material for synthesizing novel chiral auxiliaries and catalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry and exploring new reaction pathways.

Basic Information

Product Name	(S)-4-Tosyloxy-1,2-Epoxybutane
CAS No.	91111-12-5
Molecular Formula	C11H14O4S
Molecular Weight	242.29 g/mol
Synonyms	(S)-1,2-Epoxy-4-(p-toluenesulfonyloxy)butane; (S)-4-(Tosyloxy)-1,2-epoxybutane; (S)-Glycidyl tosylate; (S)-Oxiran-2-ylmethyl 4-methylbenzenesulfonate; (2S)-2-[(4-Methylphenyl)sulfonyloxymethyl]oxirane; (S)-Epibromohydrin Tosylate Analog; (S)-ETOA
EINECS	Contact for details

Quality Control

Our (S)-4-Tosyloxy-1,2-Epoxybutane is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity suitable for advanced synthetic applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.