Description

11α,12α-Bis(Acetyloxy)-15-[(Z)-1-Hydroxy-2-Methylpropylidene]Phragmalin 30-Acetate 3-(2-Hydroxy-2-Methylpropionate) is a complex, highly functionalized limonoid derivative, a class of compounds known for their significant bioactivity. This compound matters as a high-purity reference standard and key intermediate for advanced research and development in pharmaceutical discovery. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and building block for the synthesis and study of novel bioactive compounds.
• Natural Product Chemistry: Used as a high-purity analytical standard for the identification and quantification of limonoids in complex plant extracts.
• Bioactivity Screening: Employed in in vitro and in vivo studies to investigate potential pharmacological properties, such as anti-inflammatory, antiviral, or anticancer activities.
• Process Chemistry Development: Acts as a key intermediate for the semi-synthesis of structurally related analogs for structure-activity relationship (SAR) studies.
• Academic Research: Utilized in university and institutional labs for fundamental studies on terpenoid biosynthesis, chemical ecology, and medicinal chemistry.
• Quality Control Laboratories: Functions as a certified reference material (CRM) to validate analytical methods like HPLC and LC-MS for purity assessment.

Basic Information

Item	Details
Product Name	11α,12α-Bis(Acetyloxy)-15-[(Z)-1-Hydroxy-2-Methylpropylidene]Phragmalin 30-Acetate 3-(2-Hydroxy-2-Methylpropionate)
CAS No.	90931-02-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	11α,12α-Bis(acetyloxy)-15-[(1Z)-1-hydroxy-2-methyl-1-propen-1-yl]-7-oxo-7,20-epoxy-1,2,6,20,22,25-hexanor-5,24:12,17-dietheno-18,21-metheno-18H-dinaphtho[2,1-d:1',2'-g][1,3,7]dioxazacyclononadecine-4,13,16-trione, 30-acetate 3-(2-hydroxy-2-methylpropanoate); Phragmalin 30-acetate 3-(2-hydroxy-2-methylpropionate) derivative; 15-[(Z)-1-Hydroxy-2-methylpropylidene]phragmalin 30-acetate 3-(2-hydroxy-2-methylpropionate); Limonoid derivative 90931-02-5; 11α,12α-Diacetoxy phragmalin ester
EINECS	Contact for details

Quality Control

Our 11α,12α-Bis(Acetyloxy)-15-[(Z)-1-Hydroxy-2-Methylpropylidene]Phragmalin 30-Acetate 3-(2-Hydroxy-2-Methylpropionate) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, spectroscopic identification (NMR, IR, MS), and residual solvent analysis, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere at lower temperatures (e.g., -20°C) to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on dried basis)
Loss on Drying	≤ 2.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.