Description

3-Phenylcyclobutanamine Hydrochloride is a high-purity organic salt of significant interest in advanced chemical synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop new molecular entities with enhanced properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require a phenylcyclobutylamine scaffold.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for the synthesis of specialized polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific molecular framework.

Basic Information

Product Name	3-Phenylcyclobutanamine Hydrochloride
CAS No.	90874-40-1
Molecular Formula	C10H14ClN
Molecular Weight	183.68 g/mol
Synonyms	3-Phenylcyclobutan-1-amine hydrochloride; 1-Amino-3-phenylcyclobutane hydrochloride; 3-Phenylcyclobutylamine HCl; Benzenamine, 3-cyclobutyl-, hydrochloride; (3-Phenylcyclobutyl)amine hydrochloride; 3-PCBA HCl; 90874-40-1; trans-3-Phenylcyclobutanamine hydrochloride (if applicable)
EINECS	Contact for details

Quality Control

Our 3-Phenylcyclobutanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.