Description

3-Oxatricyclo[2.2.1.02,6]Heptane-1-Carboxylicacid,5-Hydroxy-,Methylester,Stereoisomer(9Ci) is a high-purity, stereochemically defined bicyclic lactone derivative, serving as a critical chiral building block and synthetic intermediate. Its unique, rigid molecular framework is essential for constructing complex pharmacophores and advanced materials with precise spatial orientation. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its stereochemistry can influence biological activity and selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the preparation of chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with specific thermal or mechanical properties derived from its strained ring system.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis and stereochemistry.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrance molecules, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	3-Oxatricyclo[2.2.1.02,6]Heptane-1-Carboxylicacid,5-Hydroxy-,Methylester,Stereoisomer(9Ci)
CAS No.	90762-16-6
Molecular Formula	C8H10O4
Molecular Weight	170.16 g/mol
Synonyms	5-Hydroxy-3-oxatricyclo[2.2.1.02,6]heptane-1-carboxylic acid methyl ester; Methyl 5-hydroxy-3-oxatricyclo[2.2.1.02,6]heptane-1-carboxylate; Bicyclic lactone methyl ester; (1R,2S,4R,5R)-Methyl 5-hydroxy-3-oxatricyclo[2.2.1.02,6]heptane-1-carboxylate (example stereoisomer); 3-Oxa-1-azatricyclo[2.2.1.02,6]heptane derivative; Norcamphor lactone ester; Contact for additional stereoisomer-specific identifiers.
EINECS	Contact for details

Quality Control

Every batch of 3-Oxatricyclo[2.2.1.02,6]Heptane-1-Carboxylicacid,5-Hydroxy-,Methylester,Stereoisomer(9Ci) is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and isomeric purity and compliance with customer specifications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e. (Specify isomer)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.