Description

Cyclobutanecarboxylic Acid, 3-(Chloroformyl)-2,2-Dimethyl-, Methyl Ester (7Ci) is a high-purity, functionalized cyclobutane derivative that serves as a critical chiral building block and advanced pharmaceutical intermediate. Its unique sterically hindered structure and reactive chloroformyl group make it invaluable for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of proprietary drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Building block for creating novel herbicides and fungicides with enhanced activity and selectivity.
• Material Science Research: Monomer or precursor for specialty polymers and advanced materials requiring rigid, cyclic structures.
• Organic Synthesis & Catalysis: Valuable substrate in methodological development for ring-opening, cross-coupling, and asymmetric synthesis reactions.
• Peptidomimetics & Bioactive Molecule Design: Used to introduce constrained, non-natural amino acid analogs into peptide chains to improve metabolic stability.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 3-(Chloroformyl)-2,2-Dimethyl-, Methyl Ester (7Ci)
CAS No.	90675-51-7
Molecular Formula	C9H13ClO3
Molecular Weight	204.65 g/mol
Synonyms	3-(Chloroformyl)-2,2-dimethylcyclobutanecarboxylic acid methyl ester; Methyl 3-(chlorocarbonyl)-2,2-dimethylcyclobutanecarboxylate; 2,2-Dimethylcyclobutane-1,3-dicarboxylic acid 1-methyl ester 3-acid chloride; (1R,3S)-rel-3-(Chloroformyl)-2,2-dimethylcyclobutanecarboxylic Acid Methyl Ester; Cyclobutane-1,3-dicarboxylic acid, 2,2-dimethyl-, 1-methyl ester 3-chloride; 7Ci derivative of cyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of Cyclobutanecarboxylic Acid, 3-(Chloroformyl)-2,2-Dimethyl-, Methyl Ester (7Ci) is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.