Description

Norvaline, 3-Fluoro-3-Methyl-, Methyl Ester is a specialized fluorinated amino acid derivative, a high-value building block in advanced organic synthesis. Its unique structure, featuring a fluorine atom on the β-carbon, makes it a critical intermediate for developing novel pharmaceuticals and bioactive compounds. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating molecules with tailored metabolic stability and biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated drug candidates, including protease inhibitors and enzyme modulators.
• Agrochemical Research: Used in the synthesis of novel fluorinated pesticides and herbicides, where the fluorine atom can enhance bioavailability and environmental persistence.
• Peptide Chemistry: Serves as a non-proteinogenic, fluorinated amino acid analog for incorporating into synthetic peptides to study structure-activity relationships and improve metabolic stability.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical and diagnostic research.
• Material Science Precursor: Acts as a specialty monomer or precursor for advanced polymeric materials with specific surface properties.

Basic Information

Product Name	Norvaline, 3-Fluoro-3-Methyl-, Methyl Ester
CAS No.	90428-01-6
Molecular Formula	C7H14FNO2
Molecular Weight	163.19 g/mol
Synonyms	Methyl 3-Fluoro-3-methylnorvalinate; 3-Fluoro-3-methyl-DL-norvaline methyl ester; 2-Amino-3-fluoro-3-methylpentanoic acid methyl ester; DL-3-Fluoro-3-methylnorvaline methyl ester; (RS)-3-Fluoro-3-methylnorvaline methyl ester; 3-Fluoro-3-methyl-norvalinic acid methyl ester; Methyl 3-fluoro-3-methyl-2-aminopentanoate
EINECS	Contact for details

Quality Control

Every batch of Norvaline, 3-Fluoro-3-Methyl-, Methyl Ester is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to verify identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.