Description

5-Chloro-2-(Trifluoromethyl)Benzaldehyde is a versatile halogenated aromatic aldehyde building block, distinguished by its trifluoromethyl and chloro substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and bioactivity.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions, such as Suzuki and Heck reactions, and as a substrate for developing new catalytic methodologies.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing specialized dyes and pigments with enhanced color fastness and stability.
• Polymer Modification: Used to introduce functional aromatic aldehydes into polymer chains, modifying thermal and chemical resistance properties.

Basic Information

Product Name	5-Chloro-2-(Trifluoromethyl)Benzaldehyde
CAS No.	90381-07-0
Molecular Formula	C8H4ClF3O
Molecular Weight	208.56 g/mol
Synonyms	5-Chloro-α,α,α-trifluoro-o-tolualdehyde; 2-Trifluoromethyl-5-chlorobenzaldehyde; 5-Chloro-2-(trifluoromethyl)benzene-1-carbaldehyde; 5-Chloro-α,α,α-trifluoro-2-methylbenzaldehyde; 5-Chloro-α,α,α-trifluoro-o-toluic aldehyde; 5-Chloro-2-trifluoromethylbenzaldehyde; 2-Carbaldehyde-5-chloro-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Trifluoromethyl)Benzaldehyde undergoes rigorous quality testing to ensure compliance with industry standards. We implement strict in-process controls and final release testing, including identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.