Description

2-Chloro-4-Fluoro-3-Methylaniline is a halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides a versatile scaffold for constructing complex molecules with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the chloro and fluoro substituents enhance biological activity.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing specialized azo dyes and organic pigments.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to create complex amine derivatives.

Basic Information

Product Name	2-Chloro-4-Fluoro-3-Methylaniline
CAS No.	90292-63-0
Molecular Formula	C7H7ClFN
Molecular Weight	159.59 g/mol
Synonyms	3-Amino-2-chloro-4-fluorotoluene; 2-Chloro-4-fluoro-3-methylbenzenamine; 3-Methyl-2-chloro-4-fluoroaniline; Benzenamine, 2-chloro-4-fluoro-3-methyl-; 2-Chloro-4-fluoro-m-toluidine; 4-Fluoro-2-chloro-3-methylaniline; 2-Chloro-4-fluoro-3-toluidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-3-Methylaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment. We are committed to meeting the stringent requirements of cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.