Description

Cyclobutanol, 3-Amino-2,2,4,4-Tetramethyl-, Hydrochloride (1:1) is a high-purity, functionalized cyclobutane derivative that serves as a valuable chiral building block and intermediate in advanced organic synthesis. Its rigid, sterically hindered structure and amine functionality make it particularly significant for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is utilized in the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its unique structure can contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties due to its strained ring system.
• Academic and R&D Laboratories: Employed as a reference standard and a specialized reagent in methodological studies and synthetic route exploration.
• Fine Chemical Production: Acts as a building block for synthesizing complex fragrance molecules, dyes, and other specialty chemicals.

Basic Information

Product Name	Cyclobutanol, 3-Amino-2,2,4,4-Tetramethyl-, Hydrochloride (1:1)
CAS No.	90226-44-1
Molecular Formula	C9H20ClNO
Molecular Weight	193.71 g/mol
Synonyms	3-Amino-2,2,4,4-tetramethylcyclobutanol hydrochloride; 2,2,4,4-Tetramethyl-3-aminocyclobutanol HCl; 1-Amino-2,2,4,4-tetramethylcyclobutanol hydrochloride; Tetramethylaminocyclobutanol hydrochloride; 3-Amino-2,2,4,4-tetramethyl-1-cyclobutanol hydrochloride; Aminotetramethylcyclobutanol HCl
EINECS	Contact for details

Quality Control

Every batch of Cyclobutanol, 3-Amino-2,2,4,4-Tetramethyl-, Hydrochloride (1:1) is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and enantiomeric excess meet the stringent requirements of our clients. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.