Description

Cm Dextranomer C-25-120 is a cross-linked, porous polysaccharide bead derived from dextran, characterized by its specific particle size range and swelling properties. This material is engineered for high-performance liquid chromatography (HPLC) and other separation techniques, offering excellent resolution and reproducibility. It is a critical component for researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors who require reliable, high-quality separation media for purification and analysis.

Application

• Size-Exclusion Chromatography (SEC/GPC): Primary matrix for the separation and molecular weight determination of proteins, polysaccharides, and synthetic polymers.
• High-Performance Liquid Chromatography (HPLC): Used as a stationary phase in analytical and preparative columns for biomolecule purification.
• Biopharmaceutical Downstream Processing: Purification of monoclonal antibodies, vaccines, and other therapeutic proteins.
• Enzyme Immobilization: Serves as a support matrix for covalently binding enzymes for use in biocatalysis and biosensors.
• Desalting and Buffer Exchange: Efficient removal of salts and small molecules from protein solutions.
• Gel Filtration Media: Standard media for laboratory-scale gel filtration chromatography.

Basic Information

Item	Details
Product Name	Cm Dextranomer C-25-120
CAS No.	9044-05-7
Molecular Formula	(C6H10O5)n
Molecular Weight	Variable (Polymer)
Synonyms	Sephadex® G-25 (coarse grade); Dextran Cross-linked; Cross-linked Dextran; Dextranomer; 2-Hydroxyethyl Methacrylate-Dextran Copolymer; Gel Filtration Beads; Size Exclusion Chromatography Media; Dextran Gel
EINECS	Contact for details

Quality Control

Our Cm Dextranomer C-25-120 is manufactured under a strict quality management system. Each batch is tested to ensure it meets precise specifications for particle size distribution, swelling coefficient, and chromatographic performance. Certificates of Analysis (COA) documenting purity, physical characteristics, and functional performance are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture uptake, which can affect performance.

Specification

Item	Specification
Appearance	White to off-white beads
Particle Size (dry)	100 - 300 μm
Swelling Coefficient (H2O)	4.0 - 6.0 ml/g dry gel
Exclusion Limit (Globular Proteins)	~5,000 Da
pH Stability Range	2 - 13
Functional Group	Carboxymethyl
Capacity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.