Description

Polydioxanone CAS NO 31621-87-1 is a synthetic, absorbable polyester derived from the monomer p-dioxanone, valued for its unique combination of strength, flexibility, and controlled biodegradability. This material is engineered to provide reliable, long-term performance in demanding medical environments where temporary structural support is critical. It is an essential polymer for manufacturers in the biomedical and pharmaceutical industries requiring high-purity, biocompatible materials for advanced therapeutic devices.

Application

• Absorbable Surgical Sutures: The primary application, used to create monofilament sutures (e.g., PDS) for soft tissue approximation and ligation, which are absorbed by hydrolysis.
• Orthopedic Fixation Devices: Used in the manufacture of pins, screws, and plates for bone fixation that gradually transfer load to healing bone as they resorb.
• Drug Delivery Systems: Serves as a matrix for controlled-release formulations, allowing for sustained and localized delivery of active pharmaceutical ingredients.
• Tissue Engineering Scaffolds: Provides a biodegradable framework to support cell growth and tissue regeneration in guided tissue repair applications.
• Vascular Applications: Employed in bioresorbable vascular stents and grafts that support vessels temporarily before being metabolized.
• Dental and Maxillofacial Surgery: Used for membranes in guided bone regeneration and as fixation devices in craniofacial reconstructive surgery.

Basic Information

Product Name	Polydioxanone
CAS No.	31621-87-1
Molecular Formula	(C4H6O3)n
Molecular Weight	Varies (Polymer)
Synonyms	Poly(p-dioxanone); PDS; Poly(1,4-dioxan-2-one); Poly(oxy-1,4-butanediyloxycarbonyl); PDX; Polydioxanone Resin; Absorbable Polymer Suture Material; Poly-Dioxanone
EINECS	Contact for details

Quality Control

Our Polydioxanone is manufactured under strict quality management systems to ensure it meets the exacting standards required for medical device and pharmaceutical applications. Each batch is tested for critical parameters including inherent viscosity, residual monomer content, molecular weight distribution, and biocompatibility to ensure consistency and performance. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the original packaging is sealed after use to prevent moisture uptake, which can affect polymer properties.

Specification

Item	Specification
Appearance	White to off-white beads or powder
Identification (IR)	Conforms to reference spectrum
Inherent Viscosity	1.5 - 2.5 dL/g (Typical, varies by grade)
Residual Monomer	≤ 1.0% (by HPLC)
Melting Point	105 - 115 °C
Moisture Content	≤ 0.5% (by KF Titration)
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Bioburden	As per required grade (USP/EP)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.