Description

Endobon is a high-purity synthetic bone graft substitute material, identified by CAS No. 158623-13-3. This advanced biomaterial is engineered to provide excellent osteoconductive properties, facilitating natural bone ingrowth and regeneration. It is essential for medical device manufacturers and research institutions focused on developing orthopedic, dental, and maxillofacial surgical solutions.

Application

• Orthopedic Bone Grafting: Used as a synthetic bone void filler in spinal fusion, trauma, and joint revision surgeries.
• Dental Implantology: Serves as a scaffold for alveolar ridge augmentation and socket preservation following tooth extraction.
• Maxillofacial Reconstruction: Applied in craniofacial defect repair and contour augmentation procedures.
• Biomedical Research: Acts as a critical substrate for in vitro and in vivo studies on bone tissue engineering and biocompatibility.
• Medical Device Coating: Utilized to enhance the osseointegration properties of metallic implants, such as hip and knee prostheses.
• Veterinary Orthopedics: Employed in advanced surgical procedures for companion and large animals.

Basic Information

Product Name	Endobon
CAS No.	158623-13-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hydroxyapatite Ceramic Granules; Synthetic Bone Graft Material; Bone Substitute Ceramic; Osteoconductive Biomaterial; HA Granules; Bioceramic Bone Graft; Porous Hydroxyapatite; Medical Grade Hydroxyapatite
EINECS	Contact for details

Quality Control

Our Endobon is manufactured under stringent quality management systems to ensure batch-to-batch consistency and compliance with relevant medical device regulations. Each lot is tested for critical parameters including purity, crystallinity, porosity, and biocompatibility. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your regulatory submissions and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture absorption, which may affect physical properties.

Specification

Item	Specification
Appearance	White to off-white granules
Identification (XRD)	Conforms to Hydroxyapatite standard
Assay (Hydroxyapatite Content)	≥ 98.0 %
Porosity	70 - 80 %
Particle Size Distribution	As per customer requirement (e.g., 0.5-1.0 mm, 1.0-2.0 mm)
Heavy Metals (ICP-MS)	< 10 ppm
Sterility (for sterile grades)	Sterile (Validated sterilization process)
Bioburden (for non-sterile grades)	< 100 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.