Description

1-Fluoro-4-(Trifluoromethylthio)Benzene is a versatile fluorinated aromatic building block characterized by its unique combination of fluorine and a trifluoromethylthio substituent. This compound is valued for its role in introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced chemical synthesis. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the SCF3 moiety.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorinated thioether group enhances biological activity.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals, contributing to unique electronic and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex aromatic systems for various R&D applications.
• Chemical Research: Utilized in academic and industrial labs to study structure-activity relationships and develop new fluorination methodologies.

Basic Information

Product Name	1-Fluoro-4-(Trifluoromethylthio)Benzene
CAS No.	940-76-1
Molecular Formula	C7H4F4S
Molecular Weight	196.17 g/mol
Synonyms	4-Fluoro(trifluoromethylthio)benzene; p-Fluorophenyl trifluoromethyl sulfide; 1-Fluoro-4-(trifluoromethylsulfanyl)benzene; 4-(Trifluoromethylthio)fluorobenzene; Benzene, 1-fluoro-4-[(trifluoromethyl)thio]-; α,α,α-Trifluoro-4-fluorothioanisole
EINECS	Contact for details

Quality Control

Our 1-Fluoro-4-(Trifluoromethylthio)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.