Description

3-Fluoro-4-(trifluoromethylthio)benzene is a high-purity fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring both fluorine and a trifluoromethylthio group, makes it a valuable intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and sulfur-containing moiety can enhance biological activity and environmental profile.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex, fluorinated biaryl systems for various R&D applications.

Basic Information

Product Name	3-Fluoro-4-(trifluoromethylthio)benzene
CAS No.	940-19-2
Molecular Formula	C7H4F4S
Molecular Weight	196.17 g/mol
Synonyms	1-Fluoro-2-((trifluoromethyl)thio)benzene; 3-Fluoro-α,α,α-trifluoro-p-toluenethiol; 4-(Trifluoromethylthio)-3-fluorobenzene; Benzene, 3-fluoro-4-[(trifluoromethyl)thio]-; 3-Fluoro-4-(trifluoromethylmercapto)benzene; 3-Fluoro-4-(trifluoromethylsulfanyl)benzene; 940-19-2
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(trifluoromethylthio)benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.