Description

4-Chloro-3-Nitrobenzonitrile is a versatile aromatic nitrile derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both chloro and nitro substituents, makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing benzimidazole or quinazoline cores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging its halogenated nitroaromatic reactivity.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing specialized azo dyes and organic pigments.
• Material Science Research: Employed in the development of liquid crystals, organic semiconductors, and polymers due to its electron-withdrawing groups.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig aminations for carbon-carbon and carbon-heteroatom bond formation.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	4-Chloro-3-Nitrobenzonitrile
CAS No.	939-80-0
Molecular Formula	C7H3ClN2O2
Molecular Weight	182.56 g/mol
Synonyms	3-Nitro-4-chlorobenzonitrile; 4-Chloro-3-nitrobenzenecarbonitrile; 1-Chloro-2-cyano-4-nitrobenzene; Benzonitrile, 4-chloro-3-nitro-; 4-Chloro-3-nitro-benzonitril; 939-80-0; 4-Chloro-3-nitrobenzonitrile; 4-Chlor-3-nitro-benzonitril
EINECS	213-365-4

Quality Control

Our 4-Chloro-3-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.