Description

2,2-Dimethylpropiophenone is a specialized aromatic ketone compound valued for its role as a key synthetic intermediate and building block in advanced organic chemistry. Its unique sterically hindered structure makes it particularly useful for introducing the tert-butylbenzoyl moiety into target molecules. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel compounds with specific properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a bulky, lipophilic aromatic group.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the 2,2-dimethylpropionyl group can influence biological activity and stability.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Employed in the synthesis of monomers and photoinitiators for specialty polymers, including UV-curable resins and coatings.
• Fragrance and Flavor Ingredient Synthesis: Utilized as an intermediate for producing aroma chemicals with specific musk or fruity notes.
• Organic Synthesis Research: A valuable building block in academic and industrial R&D for constructing complex molecular architectures, including natural product analogs.

Basic Information

Product Name	2,2-Dimethylpropiophenone
CAS No.	938-16-9
Molecular Formula	C11H14O
Molecular Weight	162.23 g/mol
Synonyms	Pivalophenone; 2,2-Dimethyl-1-phenyl-1-propanone; α,α-Dimethylpropiophenone; tert-Butyl phenyl ketone; Phenyl tert-butyl ketone; 1-Phenyl-2,2-dimethyl-1-propanone; 938-16-9; NSC 66427
EINECS	213-340-7

Quality Control

Our 2,2-Dimethylpropiophenone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Approx. 19 - 21 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.