Description

trans-2-Methylcyclohexylamine is a chiral, alicyclic amine of significant industrial interest. This compound serves as a versatile building block and chiral auxiliary in the synthesis of complex molecules, offering a rigid cyclohexane backbone for stereochemical control. It is particularly valuable for manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop optically active intermediates, catalysts, and ligands. Its unique structural properties make it a key reagent for asymmetric synthesis and the production of high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs and other therapeutic agents requiring stereochemical purity.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and fungicides where the specific stereoisomer can be critical for biological activity and environmental safety.
• Catalyst and Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric hydrogenation, alkylation, and other enantioselective transformations.
• Specialty Polymer Modifier: Employed as a curing agent or chain modifier in the production of specialty polyamides, epoxies, and other polymers to impart specific thermal or mechanical properties.
• Corrosion Inhibitor Formulation: A component in formulations for metalworking fluids and industrial coatings where its amine functionality provides protective properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	trans-2-Methylcyclohexylamine
CAS No.	931-10-2
Molecular Formula	C7H15N
Molecular Weight	113.20 g/mol
Synonyms	(1R,2R)-2-Methylcyclohexanamine; (1S,2S)-2-Methylcyclohexanamine; trans-2-Methylcyclohexanamine; 2-Methylcyclohexylamine, trans-; (±)-trans-2-Methylcyclohexylamine; Cyclohexanamine, 2-methyl-, trans-; 2-Methylcyclohexanamine; NSC 60548
EINECS	213-232-7

Quality Control

Our trans-2-Methylcyclohexylamine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, containers must be kept tightly sealed to exclude moisture. Store away from strong oxidizers and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0% (trans-isomer)
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.