Description

3-Chlorocarbonyl-2,2-dimethylpropanoic acid is a versatile chlorinated organic acid derivative with significant utility as a key synthetic intermediate. Its bifunctional nature, featuring both a carboxylic acid and an acid chloride group, makes it a valuable building block for constructing complex molecules in fine chemical synthesis. This compound, identified by Inchi=1/C5H9Clo2/C1-3(2)4(6)5(7)8/H3-4H,1-2H3,(H,7,8, is essential for manufacturers in the pharmaceutical, agrochemical, and polymer industries seeking to introduce specific functional groups with high precision.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the 3-chloro-2,2-dimethylpropionyl moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its reactive groups enable the formation of amide or ester linkages.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for specialty polymers, including polyesters and polyamides, imparting specific thermal or chemical resistance properties.
• Fine Chemical Production: Employed in the manufacture of complex organic compounds, dyes, and pigments, leveraging its reactivity for selective acylation reactions.
• Bioconjugation Reagent: Utilized in biochemical research and diagnostic kit development for labeling proteins or other biomolecules.
• Liquid Crystal & OLED Material Synthesis: Functions as a building block for advanced electronic materials requiring specific chlorinated aromatic-aliphatic structures.

Basic Information

Product Name	3-Chlorocarbonyl-2,2-dimethylpropanoic acid
CAS No.	921-08-4
Molecular Formula	C5H7ClO3
Molecular Weight	150.56 g/mol
Synonyms	3-Chloro-2,2-dimethyl-3-oxopropanoic acid; 3-Chloro-2,2-dimethylmalonic acid monoacyl chloride; 2,2-Dimethyl-3-chlorocarbonylpropanoic acid; 3-(Chlorocarbonyl)-2,2-dimethylpropanoic acid; Dimethylmalonyl chloride monoacid; NSC 9375; 3-Chloro-3-oxo-2,2-dimethylpropanoic acid
EINECS	Contact for details

Quality Control

Our production of 3-Chlorocarbonyl-2,2-dimethylpropanoic acid adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all critical parameters are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its reactivity as a strong acid/organic solvent derivative, keep away from heat, open flames, and incompatible materials such as bases, amines, and oxidizing agents. Containers should be kept tightly sealed when not in use to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	85 - 90 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.