Description

2-Hydroxy-2-Methyl-3-Oxobutanoicacid is a versatile organic compound that serves as a key building block in fine chemical synthesis. Its unique structure, featuring both hydroxyl and ketone functional groups, makes it a valuable intermediate for creating more complex molecules. This chemical is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-purity intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring specific chiral or branched-chain structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, contributing to enhanced crop protection formulations.
• Fine Chemical Manufacturing: Serves as a building block for dyes, pigments, flavors, and fragrances, where precise molecular architecture is required.
• Biochemical Research: Employed in metabolic pathway studies and as a substrate or intermediate in enzymatic reactions and fermentation processes.
• Polymer Chemistry: Acts as a monomer or cross-linking agent modifier for specialty polymers, influencing properties like biodegradability or adhesion.
• Chelating Agent Precursor: Its functional groups can be utilized to develop ligands for metal complexation in various industrial and analytical applications.

Basic Information

Product Name	2-Hydroxy-2-Methyl-3-Oxobutanoicacid
CAS No.	918-44-5
Molecular Formula	C5H8O4
Molecular Weight	132.11 g/mol
Synonyms	2-Hydroxy-2-methyl-3-oxobutanoic acid; 2-Methyl-2-hydroxy-3-oxobutanoic acid; Acetoacetic acid, 2-hydroxy-2-methyl-; 2-Hydroxy-2-methylacetoacetic acid; α-Hydroxy-α-methylacetoacetic acid; 2-Hydroxyisovaleric acid β-keto acid; 918-44-5; Oxobutanoic acid, 2-hydroxy-2-methyl-
EINECS	213-041-1

Quality Control

We maintain rigorous quality control protocols for 2-Hydroxy-2-Methyl-3-Oxobutanoicacid to ensure batch-to-batch consistency and high purity suitable for demanding synthesis applications. Our standard grade typically meets a purity specification of ≥98% (by HPLC). Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles. We can support production under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.