Description

4'-Chloroacetophenone is a versatile aromatic ketone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its reactive carbonyl and chlorinated aromatic ring, which enable precise chemical transformations for creating complex molecules. This intermediate is essential for manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop active ingredients and specialty compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including certain antihistamines and central nervous system agents.
• Agrochemical Synthesis: Used in the production of herbicides, pesticides, and plant growth regulators, leveraging its halogenated structure.
• Fine Chemical Manufacturing: Serves as a starting material for dyes, pigments, and photoinitiators used in polymer and coating industries.
• Organic Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.
• Fragrance and Flavor Intermediate: Employed in the controlled synthesis of specific aromatic compounds for specialty applications.

Basic Information

Item	Details
Product Name	4'-Chloroacetophenone
CAS No.	99-91-2
Molecular Formula	C8H7ClO
Molecular Weight	154.59 g/mol
Synonyms	p-Chloroacetophenone; 4-Chloroacetophenone; 1-(4-Chlorophenyl)ethanone; Methyl 4-chlorophenyl ketone; p-Chlorophenyl methyl ketone; 4-Chlorophenyl methyl ketone; Acetophenone, 4'-chloro-; NSC 406908
EINECS	202-802-8

Quality Control

Our 4'-Chloroacetophenone is produced under a rigorous quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78°C - 82°C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.