Description

6-Isoquinolinyl-Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient formation of carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, especially those containing the isoquinoline scaffold.
• Suzuki-Miyaura Cross-Coupling Reagent: Used extensively in palladium-catalyzed reactions to create biaryl and heterobiaryl structures central to many active molecules.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides with specific targeting properties.
• Material Science: Serves as a precursor for creating advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized in the development of chemical probes and inhibitors for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthesis projects requiring high-fidelity coupling reactions.

Basic Information

Product Name	6-Isoquinolinyl-Boronic Acid
CAS No.	899438-92-7
Molecular Formula	C9H8BNO2
Molecular Weight	173.98 g/mol
Synonyms	6-Isoquinolineboronic Acid; (Isoquinolin-6-yl)boronic Acid; B-(6-Isoquinolinyl)boronic Acid; 6-Boronisoquinoline; 6-Isoquinolylboronic Acid; Isoquinoline-6-boronic Acid; 899438-92-7; Boronic acid, B-6-isoquinolinyl-
EINECS	Contact for details

Quality Control

Our 6-Isoquinolinyl-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including HPLC purity, NMR confirmation, and heavy metal screening. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality management system supports compliance with cGMP and ISO standards for research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and hydrolysis. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.