Description

3',4'-Difluoro-3-(2,4-Dimethylphenyl)Propiophenone is a high-value, specialized organic intermediate featuring a difluorinated aromatic ketone structure. This compound is critical for its role as a key building block in advanced organic synthesis, enabling the introduction of specific fluorinated and aromatic motifs. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated bioisosteres for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and insecticides, where the difluoro and dimethylphenyl groups contribute to specific biological activity and environmental persistence profiles.
• Material Science Research: Used in the development of advanced organic materials, such as liquid crystals or organic semiconductors, where its molecular structure can influence electronic properties and self-assembly.
• Chemical Research & Development: Employed in academic and industrial R&D settings for methodological studies in cross-coupling reactions, fluorination chemistry, and the construction of complex polycyclic structures.
• Custom Synthesis & Contract Manufacturing: A vital component for fine chemical manufacturers offering bespoke synthesis services for clients in life sciences and specialty chemicals.

Basic Information

Item	Details
Product Name	3',4'-Difluoro-3-(2,4-Dimethylphenyl)Propiophenone
CAS No.	898794-56-4
Molecular Formula	C17H16F2O
Molecular Weight	274.31 g/mol
Synonyms	1-(3,4-Difluorophenyl)-3-(2,4-dimethylphenyl)propan-1-one; 3-(2,4-Dimethylphenyl)-1-(3,4-difluorophenyl)propan-1-one; 3',4'-Difluoro-3-(2,4-dimethylphenyl)propiophenone; 898794-56-4; Propiophenone, 3',4'-difluoro-3-(2,4-dimethylphenyl)-; 3-(2,4-Dimethylphenyl)-1-(3,4-difluorophenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 3',4'-Difluoro-3-(2,4-Dimethylphenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our commitment to cGMP principles ensures reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.