Description

3'-Piperidinomethyl-3,4,5-Trifluorobenzophenone is a high-value, multi-fluorinated benzophenone derivative that serves as a critical advanced pharmaceutical intermediate. Its molecular architecture, featuring a piperidine moiety and a trifluoromethylphenyl group, makes it an essential building block for synthesizing complex bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly in central nervous system (CNS) and metabolic disorder therapeutic areas.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting protein kinases and G-protein-coupled receptors (GPCRs).
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the stability imparted by the fluorine atoms.
• Material Science: Serves as a monomer or cross-linking agent in the research of specialty polymers with enhanced thermal and chemical resistance.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis due to its versatile reactive sites.
• Bioconjugation & Probe Development: Useful in creating fluorescent probes or affinity labels for biochemical and diagnostic applications.

Basic Information

Product Name	3'-Piperidinomethyl-3,4,5-Trifluorobenzophenone
CAS No.	898793-64-1
Molecular Formula	C19H18F3NO
Molecular Weight	333.35 g/mol
Synonyms	3,4,5-Trifluoro-3'-(piperidinomethyl)benzophenone; (3,4,5-Trifluorophenyl)[3-(piperidin-1-ylmethyl)phenyl]methanone; 1-({[3-(3,4,5-Trifluorobenzoyl)phenyl]methyl})piperidine; 3,4,5-Trifluoro-3'-(N-piperidylmethyl)benzophenone; 898793-64-1; Benzophenone, 3,4,5-trifluoro-3'-(piperidinomethyl)-
EINECS	Contact for details

Quality Control

Every batch of 3'-Piperidinomethyl-3,4,5-Trifluorobenzophenone is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing all critical parameters for your quality assurance review.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in its original packaging to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.