Description

3',4'-Difluoro-3-(2,3-Dimethylphenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its precise molecular architecture, featuring strategically placed fluorine atoms and a dimethylphenyl group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by pharmaceutical R&D and agrochemical development teams for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a sophisticated intermediate in the production of fluorinated compounds for electronic display and lighting applications.
• Advanced Polymer Chemistry: Employed to introduce fluorinated aromatic units into polymer backbones, modifying thermal stability, chemical resistance, and optical properties.
• Organic Synthesis Research: A valuable reagent for academic and industrial research in developing new fluorination methodologies and cross-coupling reactions.

Basic Information

Product Name	3',4'-Difluoro-3-(2,3-Dimethylphenyl)Propiophenone
CAS No.	898793-35-6
Molecular Formula	C17H16F2O
Molecular Weight	274.31 g/mol
Synonyms	1-(3,4-Difluorophenyl)-3-(2,3-dimethylphenyl)propan-1-one; 3-(2,3-Dimethylphenyl)-1-(3,4-difluorophenyl)-1-propanone; 3',4'-Difluoro-3-(2,3-dimethylphenyl)propiophenone; 898793-35-6; Propiophenone, 3',4'-difluoro-3-(2,3-dimethylphenyl)-; 1-Propanone, 1-(3,4-difluorophenyl)-3-(2,3-dimethylphenyl)-
EINECS	Contact for details

Quality Control

We maintain a strict quality management system aligned with cGMP principles for advanced intermediates. Every batch of 3',4'-Difluoro-3-(2,3-Dimethylphenyl)Propiophenone undergoes comprehensive analytical characterization using HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.