Description

3'-Chloro-3-(2,3-Dimethylphenyl)-5'-Fluoropropiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is of significant commercial importance for its role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors engaged in developing new drug candidates and proprietary synthetic routes.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a critical building block for the development of novel APIs, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, or other specialized therapeutics.
• Organic Chemistry Research: Used in academic and industrial R&D laboratories for method development, catalysis studies, and exploring new chemical reactions involving halogenated ketones.
• Fine Chemical Production: Employed in the multi-step synthesis of complex organic molecules for agrochemicals, dyes, or functional materials.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in pharmaceutical manufacturing.

Basic Information

Product Name	3'-Chloro-3-(2,3-Dimethylphenyl)-5'-Fluoropropiophenone
CAS No.	898793-19-6
Molecular Formula	C17H16ClFO
Molecular Weight	290.76 g/mol
Synonyms	1-(3-Chloro-5-fluorophenyl)-3-(2,3-dimethylphenyl)propan-1-one; 3'-Chloro-5'-fluoro-3-(2,3-dimethylphenyl)propiophenone; 898793-19-6; Propiophenone, 3'-chloro-3-(2,3-dimethylphenyl)-5'-fluoro-; 3-(2,3-Dimethylphenyl)-1-(3-chloro-5-fluorophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 3'-Chloro-3-(2,3-Dimethylphenyl)-5'-Fluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring material for GMP intermediates and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.