Description

4'-Bromo-3-(2,3-Dimethylphenyl)-2'-Fluoropropiophenone is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally defined building block essential for research and development in modern medicinal chemistry. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical producers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• API Synthesis: Employed in the controlled synthesis of complex target molecules requiring specific bromo and fluoro substitutions on a propiophenone scaffold.
• Contract Manufacturing: Supplied to CMOs for the scale-up and cGMP production of investigational and commercial pharmaceuticals.
• Chemical Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4'-Bromo-3-(2,3-Dimethylphenyl)-2'-Fluoropropiophenone
CAS No.	898793-13-0
Molecular Formula	C17H16BrFO
Molecular Weight	335.21 g/mol
Synonyms	2'-Fluoro-4'-bromo-3-(2,3-dimethylphenyl)propiophenone; 1-(4-Bromo-2-fluorophenyl)-3-(2,3-dimethylphenyl)propan-1-one; 898793-13-0; 4'-Bromo-2'-fluoro-3-(2,3-dimethylphenyl)propiophenone; 3-(2,3-Dimethylphenyl)-1-(4-bromo-2-fluorophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3-(2,3-Dimethylphenyl)-2'-Fluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards expected for pharmaceutical development, supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.