Description

2-Chloro-4-Fluorophenyl Cyclopentyl Ketone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly within pharmaceutical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a halogenated cyclopentyl ketone moiety into their target structures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new generation herbicides and fungicides, where the fluorinated aromatic structure can enhance bioavailability and environmental stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Precursor: Employed in the research and development of advanced polymers and liquid crystals with specific optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Chloro-4-Fluorophenyl Cyclopentyl Ketone
CAS No.	898791-70-3
Molecular Formula	C12H12ClFO
Molecular Weight	226.67 g/mol
Synonyms	2-Chloro-4-fluorocyclopentyl phenyl ketone; Cyclopentyl 2-chloro-4-fluorophenyl ketone; 1-(2-Chloro-4-fluorophenyl)cyclopentan-1-one; (2-Chloro-4-fluorophenyl)(cyclopentyl)methanone; 898791-70-3; Ketone, 2-chloro-4-fluorophenyl cyclopentyl; 2-Chloro-4-fluoro-1-cyclopentyl-1-phenylmethanone
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Fluorophenyl Cyclopentyl Ketone is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.