Description

Cyclobutyl 3,4,5-Trifluorophenyl Ketone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the cyclobutyl and trifluoromethylphenyl moieties, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Serves as a versatile building block for creating novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and metabolic stability.
• Liquid Crystal & OLED Material Research: Used in the synthesis of advanced organic electronic materials, where its rigid, fluorinated structure can influence mesomorphic and photophysical properties.
• Advanced Polymer Chemistry: Employed as a monomer or cross-linking agent in the development of specialty polymers with enhanced thermal and chemical resistance.
• Chemical Biology & Probe Development: Useful for creating molecular probes and tags due to the distinctive spectroscopic signature imparted by the fluorine atoms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	Cyclobutyl 3,4,5-Trifluorophenyl Ketone
CAS No.	898791-32-7
Molecular Formula	C11H9F3O
Molecular Weight	214.18 g/mol
Synonyms	1-(3,4,5-Trifluorophenyl)-1-cyclobutylmethanone; 3,4,5-Trifluorophenyl Cyclobutyl Ketone; Cyclobutyl(3,4,5-trifluorophenyl)methanone; 3,4,5-Trifluorobenzoylcyclobutane; (3,4,5-Trifluorophenyl)(cyclobutyl)methanone; Ketone, cyclobutyl 3,4,5-trifluorophenyl; 898791-32-7
EINECS	Contact for details

Quality Control

Our Cyclobutyl 3,4,5-Trifluorophenyl Ketone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.