Description

Cyclobutyl 3,5-Difluorophenyl Ketone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a strained cyclobutyl ring with a difluorinated phenyl group, enabling precise modulation of electronic and steric properties in target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of monomers and polymers with tailored properties for specialty coatings and electronic materials.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in biochemical research.
• Custom Synthesis and Scale-up: Supplied for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	Cyclobutyl 3,5-Difluorophenyl Ketone
CAS No.	898791-30-5
Molecular Formula	C11H10F2O
Molecular Weight	196.19 g/mol
Synonyms	1-(3,5-Difluorophenyl)-1-cyclobutylmethanone; 3,5-Difluorophenyl Cyclobutyl Ketone; Cyclobutyl(3,5-difluorophenyl)methanone; (3,5-Difluorophenyl)(cyclobutyl)methanone; 898791-30-5; Cyclobutyl 3,5-Difluorobenzene Ketone
EINECS	Contact for details

Quality Control

Our Cyclobutyl 3,5-Difluorophenyl Ketone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.