Description

2'-Chloro-4'-Fluoro-3-(3-Methylphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is of significant value in modern organic synthesis, particularly for constructing complex molecular frameworks requiring precise substitution patterns. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new generation herbicides and pesticides, leveraging its halogenated phenylpropiophenone core.
• Organic Synthesis: Serves as a versatile precursor for cross-coupling reactions, such as Suzuki or Heck reactions, to create more complex biaryl structures.
• Material Science: Potential monomer or precursor in the research of specialty polymers and liquid crystals due to its rigid, substituted aromatic system.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2'-Chloro-4'-Fluoro-3-(3-Methylphenyl)Propiophenone
CAS No.	898791-14-5
Molecular Formula	C16H14ClFO
Molecular Weight	276.73 g/mol
Synonyms	1-(2-Chloro-4-fluorophenyl)-3-(3-methylphenyl)-1-propanone; 3'-Methyl-2'-chloro-4'-fluoropropiophenone; 2-Chloro-4-fluoro-3'-(3-methylphenyl)propiophenone; 898791-14-5; Propiophenone, 2'-chloro-4'-fluoro-3-(3-methylphenyl)-; 1-Propanone, 1-(2-chloro-4-fluorophenyl)-3-(3-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 2'-Chloro-4'-Fluoro-3-(3-Methylphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.