Description

3-(3-Methylphenyl)-2'-Trifluoromethylpropiophenone is a specialized organic intermediate featuring a trifluoromethyl group and a propiophenone backbone. This compound is valued for its role in the synthesis of advanced pharmaceutical and agrochemical molecules, where the trifluoromethyl moiety can significantly enhance biological activity and metabolic stability. It is primarily sought by research and development chemists, as well as process development teams, in the fine chemical, pharmaceutical, and crop protection industries for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethylated aromatic system for enhanced potency and drug-like properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the introduction of fluorine atoms can improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor in the development of specialty polymers and advanced organic materials with unique electronic or surface properties.
• Ligand and Catalyst Development: Employed in organic chemistry research for the creation of novel ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on the incorporation and reactivity of fluorine in organic molecules.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	3-(3-Methylphenyl)-2'-Trifluoromethylpropiophenone
CAS No.	898791-02-1
Molecular Formula	C17H15F3O
Molecular Weight	292.30 g/mol
Synonyms	1-[3-Methylphenyl]-3-[2-(trifluoromethyl)phenyl]propan-1-one; 3-(3-Methylphenyl)-1-[2-(trifluoromethyl)phenyl]propan-1-one; 2'-Trifluoromethyl-3-(m-tolyl)propiophenone; 3-(m-Tolyl)-2'-(trifluoromethyl)propiophenone; m-Methyl-β-(2-trifluoromethylbenzoyl)ethylbenzene; 898791-02-1; Propiophenone, 3-(3-methylphenyl)-2'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 3-(3-Methylphenyl)-2'-Trifluoromethylpropiophenone adheres to stringent quality management protocols. Every batch is analyzed using advanced chromatographic and spectroscopic techniques to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality system is designed to support cGMP compliance for pharmaceutical applications and meets the rigorous standards required for global industrial and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.