Description

Cyclobutyl 3-Trifluoromethylphenyl Ketone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a cyclobutyl ring and a trifluoromethylphenyl group, makes it a valuable precursor for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals, where the rigid cyclobutyl and fluorinated aromatic units can influence material properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes in biochemical research.

Basic Information

Product Name	Cyclobutyl 3-Trifluoromethylphenyl Ketone
CAS No.	898790-97-1
Molecular Formula	C12H11F3O
Molecular Weight	228.21 g/mol
Synonyms	1-(3-(Trifluoromethyl)phenyl)cyclobutan-1-one; 3-Trifluoromethyl Cyclobutyl Phenyl Ketone; Cyclobutyl(3-(trifluoromethyl)phenyl)methanone; (3-Trifluoromethylphenyl)cyclobutyl ketone; m-Trifluoromethylphenyl cyclobutyl ketone; α-Cyclobutyl-m-(trifluoromethyl)acetophenone; Ketone, cyclobutyl 3-trifluoromethylphenyl
EINECS	Contact for details

Quality Control

Our Cyclobutyl 3-Trifluoromethylphenyl Ketone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.