Description

2-Fluorophenyl Cyclobutyl Ketone is a versatile fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, combining a fluorinated phenyl ring with a strained cyclobutyl moiety, which is crucial for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom and ketone functionality can enhance bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes used in biochemical assays and imaging.
• Academic & Contract Research: A valuable reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	2-Fluorophenyl Cyclobutyl Ketone
CAS No.	898790-94-8
Molecular Formula	C11H11FO
Molecular Weight	178.20 g/mol
Synonyms	Cyclobutyl(2-fluorophenyl)methanone; 1-(2-Fluorophenyl)-1-cyclobutylmethanone; 2-Fluorobenzoylcyclobutane; 2-Fluoro-α-cyclobutylbenzyl alcohol ketone; o-Fluorophenyl cyclobutyl ketone; 2-Fluorophenyl cyclobutyl ketone; Ketone, 2-fluorophenyl cyclobutyl
EINECS	Contact for details

Quality Control

Every batch of 2-Fluorophenyl Cyclobutyl Ketone is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to ensure consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.