Description

3'-Chloro-4'-Fluoro-3-(3-Methylphenyl)Propiophenone CAS NO 898790-93-7 is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its precise molecular architecture enables targeted pharmacological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides and pesticides with specific activity profiles.
• Material Science Research: Used in academic and industrial R&D for creating specialized polymers and liquid crystals with unique optical properties.
• Organic Synthesis: A versatile reagent for constructing complex molecular frameworks in medicinal chemistry and process chemistry.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of APIs.
• Reference Standard: Utilized as an analytical standard for quality control and method development in regulatory submissions.

Basic Information

Product Name	3'-Chloro-4'-Fluoro-3-(3-Methylphenyl)Propiophenone
CAS No.	898790-93-7
Molecular Formula	C16H14ClFO
Molecular Weight	276.73 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)-3-(3-methylphenyl)propan-1-one; 3'-Chloro-4'-fluoro-3-(m-tolyl)propiophenone; 3-(3-Methylphenyl)-1-(3-chloro-4-fluorophenyl)propan-1-one; Propiophenone, 3'-chloro-4'-fluoro-3-(3-methylphenyl)-; m-Tolyl 3-chloro-4-fluorobenzyl ketone derivative; CFMPP (abbreviation); CAS 898790-93-7
EINECS	Contact for details

Quality Control

Our 3'-Chloro-4'-Fluoro-3-(3-Methylphenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.