Description

3-Chloro-4-Fluorophenyl Cyclobutyl Ketone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. This compound is valued for its unique structural features, which enable the introduction of both halogen and cyclobutyl motifs into complex molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Chloro-4-Fluorophenyl Cyclobutyl Ketone
CAS No.	898790-88-0
Molecular Formula	C11H10ClFO
Molecular Weight	212.65 g/mol
Synonyms	Cyclobutyl(3-chloro-4-fluorophenyl)methanone; 1-(3-Chloro-4-fluorophenyl)cyclobutan-1-one; 3-Chloro-4-fluorobenzoylcyclobutane; 898790-88-0; 3-Chloro-4-fluoro cyclobutyl phenyl ketone; Ketone, 3-chloro-4-fluorophenyl cyclobutyl
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluorophenyl Cyclobutyl Ketone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and regulated development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.