Description

4'-Bromo-3'-Fluoro-3-(3-Methylphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Serves as a key building block for constructing complex molecular frameworks found in potential active pharmaceutical ingredients.
• Agrochemical Research: Used in the development and synthesis of new pesticides, herbicides, or fungicides due to its halogenated phenylpropiophenone core.
• Material Science: Potential monomer or precursor for creating specialized polymers or liquid crystals with unique optical or electronic properties.
• Chemical Research: Employed in organic synthesis for cross-coupling reactions, such as Suzuki or Heck reactions, leveraging the bromo and fluoro substituents.
• Dye & Pigment Intermediate: Can be utilized in the synthesis of complex organic dyes and pigments where specific halogen atoms are required for color or stability.

Basic Information

Product Name	4'-Bromo-3'-Fluoro-3-(3-Methylphenyl)Propiophenone
CAS No.	898790-87-9
Molecular Formula	C16H14BrFO
Molecular Weight	321.19 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)-3-(3-methylphenyl)propan-1-one; 3'-Methyl-4'-bromo-3-fluoropropiophenone; 4-Bromo-3-fluoro-3'-(3-methylphenyl)propiophenone; 3-(3-Methylphenyl)-1-(4-bromo-3-fluorophenyl)propan-1-one; Propiophenone, 4'-bromo-3'-fluoro-3-(3-methylphenyl)-; 898790-87-9; 4'-Bromo-3'-fluoro-3-(m-tolyl)propiophenone
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3'-Fluoro-3-(3-Methylphenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.