Description

4-(3-Iodophenyl)-4-Oxobutyric Acid is a high-purity iodinated aromatic ketone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile molecular scaffold for constructing complex pharmacophores and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its halogenated aromatic structure.
• Ligand & Catalyst Synthesis: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Intermediate in the production of advanced polymers and liquid crystals where iodophenyl groups impart specific electronic properties.
• Chemical Biology: Useful as a probe or tag in bioconjugation chemistry due to the reactivity of the iodine atom and carboxylic acid group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in multi-step custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	4-(3-Iodophenyl)-4-Oxobutyric Acid
CAS No.	898790-80-2
Molecular Formula	C10H9IO3
Molecular Weight	304.08 g/mol
Synonyms	4-(3-Iodophenyl)-4-oxobutanoic Acid; 3'-Iodobenzoylpropionic Acid; 4-(3-Iodobenzoyl)butyric Acid; γ-Oxo-3-iodobenzenebutanoic Acid; 4-Oxo-4-(3-iodophenyl)butyric Acid; 898790-80-2; Butanoic acid, 4-oxo-4-(3-iodophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 4-(3-Iodophenyl)-4-Oxobutyric Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.