Description

Cyclopropyl 3,4,5-Trifluorophenyl Ketone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound is valued for its unique structural motif, which combines a reactive ketone group with a cyclopropyl ring and a perfluorinated aromatic system, enabling precise molecular modifications. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Serves as a versatile precursor in the design and synthesis of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials that require fluorinated aromatic components for specific thermal or chemical resistance properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the synthesis of novel ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Chemical Biology Probes: Acts as a building block for creating molecular probes and tags used in biochemical and cellular research to study protein interactions and metabolic pathways.

Basic Information

Product Name	Cyclopropyl 3,4,5-Trifluorophenyl Ketone
CAS No.	898790-36-8
Molecular Formula	C10H7F3O
Molecular Weight	200.16 g/mol
Synonyms	1-Cyclopropyl-2-(3,4,5-trifluorophenyl)ethanone; (3,4,5-Trifluorophenyl) cyclopropyl ketone; Cyclopropyl(3,4,5-trifluorophenyl)methanone; 3,4,5-Trifluorophenyl cyclopropyl ketone; 2-Cyclopropyl-1-(3,4,5-trifluorophenyl)ethanone; Ketone, cyclopropyl 3,4,5-trifluorophenyl; CAS 898790-36-8
EINECS	Contact for details

Quality Control

Our Cyclopropyl 3,4,5-Trifluorophenyl Ketone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to cGMP and ISO standards guarantees a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.