Description

3-(2-Methylphenyl)-3',4',5'-Trifluoropropiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a substituted phenyl ring with a trifluorinated propiophenone moiety, enabling precise modifications in complex molecule construction. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atoms can improve lipophilicity, membrane permeability, and overall biological activity.
• Liquid Crystal & OLED Material Research: Serves as a precursor or intermediate in the synthesis of fluorinated organic compounds for electronic applications, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed as a monomer or functionalization agent to introduce fluorinated phenyl groups into polymer backbones, potentially altering material properties like chemical resistance, thermal stability, and optical characteristics.
• Chemical Research & Development: A versatile scaffold for method development in cross-coupling reactions, carbonyl chemistry, and fluorination studies within academic and industrial R&D laboratories.

Basic Information

Product Name	3-(2-Methylphenyl)-3',4',5'-Trifluoropropiophenone
CAS No.	898790-17-5
Molecular Formula	C₁₆H₁₃F₃O
Molecular Weight	278.27 g/mol
Synonyms	1-(3,4,5-Trifluorophenyl)-3-(o-tolyl)propan-1-one; 3-(2-Methylphenyl)-1-(3,4,5-trifluorophenyl)propan-1-one; 3',4',5'-Trifluoro-3-(2-methylphenyl)propiophenone; o-Methyl-3,4,5-trifluoropropiophenone; 898790-17-5; Propiophenone, 3-(2-methylphenyl)-3',4',5'-trifluoro-
EINECS	Contact for details

Quality Control

Our production of 3-(2-Methylphenyl)-3',4',5'-Trifluoropropiophenone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and quantify purity. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.