Description

Cyclopropyl 2-Trifluoromethylphenyl Ketone is a high-value fluorinated aromatic ketone building block, distinguished by its cyclopropyl and trifluoromethyl substituents. This compound is essential for medicinal chemistry research and development, offering unique electronic and steric properties that can significantly influence the biological activity and metabolic stability of target molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Material Science Precursor: Serves as a building block for specialty polymers and advanced organic materials requiring specific fluorinated motifs.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Cyclopropyl 2-Trifluoromethylphenyl Ketone
CAS No.	898790-12-0
Molecular Formula	C11H9F3O
Molecular Weight	214.18 g/mol
Synonyms	2-(Trifluoromethyl)phenyl cyclopropyl ketone; 1-Cyclopropyl-2-(trifluoromethyl)phenylmethanone; [2-(Trifluoromethyl)phenyl](cyclopropyl)methanone; Cyclopropyl(o-trifluoromethylphenyl)ketone; o-Trifluoromethylphenyl cyclopropyl ketone; 2-Trifluoromethyl Cyclopropyl Phenyl Ketone
EINECS	Contact for details

Quality Control

Our Cyclopropyl 2-Trifluoromethylphenyl Ketone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.