Description

3',4'-Difluoro-3-(2-Methylphenyl)Propiophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in its precise molecular structure, which serves as a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials. The product is supplied with a CAS number of 898790-11-9.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of fluorine atoms.
• Material Science Precursor: Serves as a monomer or precursor for advanced polymers and liquid crystals, where the difluoro and methylphenyl groups impart specific electronic and physical characteristics.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, carbonyl chemistry, and fluorination studies to create complex molecular architectures in academic and industrial R&D settings.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in laboratories.

Basic Information

Product Name	3',4'-Difluoro-3-(2-Methylphenyl)Propiophenone
CAS No.	898790-11-9
Molecular Formula	C16H14F2O
Molecular Weight	260.28 g/mol
Synonyms	1-(3,4-Difluorophenyl)-3-(2-methylphenyl)propan-1-one; 3-(2-Methylphenyl)-1-(3,4-difluorophenyl)-1-propanone; 3,4-Difluoro-3'-(2-methylphenyl)propiophenone; 3',4'-Difluoro-3-(o-tolyl)propiophenone; Propiophenone, 3',4'-difluoro-3-(2-methylphenyl)-; 898790-11-9; 3-(2-Methylphenyl)-1-(3,4-difluorophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 3',4'-Difluoro-3-(2-Methylphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and production needs with reliable, high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.