Description

3-Chloro-4-Fluorophenyl Cyclopropyl Ketone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both halogen and cyclopropyl substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a crucial building block for creating advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated aromatic ring.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to develop new ligands and catalysts for asymmetric synthesis.
• Material Science Research: Employed as a monomer or precursor in the synthesis of specialty polymers and advanced organic materials with specific electronic or optical properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	3-Chloro-4-Fluorophenyl Cyclopropyl Ketone
CAS No.	898790-09-5
Molecular Formula	C10H8ClFO
Molecular Weight	198.62 g/mol
Synonyms	Cyclopropyl 3-Chloro-4-fluorophenyl ketone; 1-(3-Chloro-4-fluorophenyl)cyclopropan-1-one; 3-Chloro-4-fluorobenzoylcyclopropane; (3-Chloro-4-fluorophenyl)(cyclopropyl)methanone; Ketone, 3-chloro-4-fluorophenyl cyclopropyl
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-Fluorophenyl Cyclopropyl Ketone is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure consistency and high purity. Our products are suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.